Journal: bioRxiv
Article Title: Virus-Like Particles: The Next Frontier in Livestock Gene Editing
doi: 10.64898/2026.03.30.715406
Figure Lengend Snippet: A : Bar graph showing ICE analysis results of targeting of SMAD4, B2M, KDM6A and TP53 in pKDNFs using Cas9 VLPs. Blue bars: INDEL scores, green bars: KO scores compared to WT control (n≥3; SD shown). B : Bar graph showing ICE analysis results of targeting of IL-10 in developed blastocysts (B1-B6) using multiplexed Cas9 VLPs. Blue bars: INDEL scores, green bars: KO scores compared to WT control. C : Detected INDELs of blastocyst 2 (B2) report that in 98% of the cases, the whole fragment was deleted.
Article Snippet: Sequencing results were analyzed for the percentage of INDELs using the online ICE analysis tool by Synthego ( https://ice.editco.bio ).
Techniques: Control